Yes. I have this working fine for quite a few Win2K machines. Make sure you follow the directions closely. Create the ODBC connection and make sure you remember to do this:
"The user and Windows machine must have the access privileges to the MySQL server on the Unix machine. This is set up with the GRANT command."
There is a good tutorial here:
http://www.devshed.com/Server_Side/MySQL/ODBC/page1.htmlNoah