I just started to play with version 5.0 - it's real slick and a nice server in a box product. The only place it falls short for my purposes is the lack of any mailing list support that I can detect. I run a small list for a user group board that explodes inbound mail to a special address and sends it out to multiple email accounts in other domains.
I can't see any simple way to do that in e-smith - right now I use Eudora's EIMS server on an old Mac, and simply define the mailing list as a small textfile with carriage returns between each entry. The address is pointed to the file and blasts e-mails from there.
I'm sure there's a way to do this with qmail that I just haven't puzzled out, but it'd be nicer if e-smith had a mail list manager that was part of the server manager. But if anyone can point me in the right direction I'd be much obliged.