Doing some digging, the current excluded directories can be found here:
# db configuration getprop clamav FilesystemScanExclude
/proc,/sys,/usr/share,/var
So to exclude, say, an i-bay, the following (entered on a single line) should work:
# db configuration setprop clamav FilesystemScanExclude '/proc,/sys,/usr/share,/var,/home/e-smith/files/ibays/<my-ibay-name>'
with <my-ibay-name> replaced as appropropriate. I don't know if that will ever get overwritten through a future upgrade, but at least it should work for now. Unfortunately the 'db' command does not have the ability to add and remove individual items from a CSV list in a property, so you have to be careful when updating it to ensure you retain any existing paths.
Hope that helps someone else wishing to exclude directories from their weekly or daily filesystem AV scan.
-- JJ