I figured it out, I just pointed an A record with a wildcard for each of my virtual domains to the static IP and an MX record to domain name with a trailing period, i.e.,
politicalbloviation.com.
SME won't handle it with mail appended to any on the virtual domains, but it does work for the primary. I tested and all seems well, an e-mail to admin@politicalbloviation ends up in the admin user acct on SME as it should.