Thanx to Google i've come a little closer....
I placed openticket.pl into the cgi-bin directory of the ibay 'incident' where the files of phpsupport are.
I've created .qmail-support at /var/qmail/aliasfilled with:
| /home/e-smith/files/ibays/incident/cgi-bin/openticket.pl
When i send an email to support@mydomain.com this shows in the logfile:
@400000004694c4613805d9ac delivery 206: deferral: /bin/sh:_/home/e-smith/files/ibays/incident/cgi-bin/openticket.pl:_Permission_denied/
I've tried chown + chmod many variations up to root:root 777 but nothing works.
What am I overlooking?