I also have had some spam relaying happening on my 7.2 system, starting around the 15th or 16th Sept. Evidenced by many hundreds of bounces coming back at me from one sender in my domain. I tried to interpret the logs, and look through qmail configuration, but it all got too hard. I'm using SMEServer in a home situation. I got around the problem by changing the ISP Smarthost setting, and setting all my PCs to send mail directly to my ISP, rather than through the SMEServer. The SPAM bounces immediately dropped off in rate. After a few days, I am now getting only the occasional notification like "still trying after 4 days".
I registered on bugzilla, but don't have permission to access #3395.
Cheers,
Mark