http://en.wikipedia.org/wiki/Bypass_your_cacheMozilla family
This includes Firefox, Netscape Navigator (versions 6.x and 7.x) and SeaMonkey.
* To reload a page and bypass the cache:
o either: Hold down both the Ctrl and Shift keys and then press R. (Alternatively, hold down the Ctrl key and then press F5.) On a Mac, use the Command key instead of Ctrl.
o or: Hold down the Shift key and click the Reload button on the navigation toolbar.
Internet Explorer
* To reload a page and bypass the cache:
o either: Hold the Ctrl key, and press F5.
o or: Hold the Ctrl key, and click the Refresh button on the Start bar.