there is definitively a bug here we need to resolve, as there is an infinity loop
I do not know how safe it is to delete from the qpsmtpd queue
I just tested and confirmed the bug on a server, I had the opposite approach,
define mail.p10361243119.s2599.jianzhanapp.com to an ip of another server I control or any ip of your lan in /etc/hosts, and then used qmail handle to delete the mail
MESSAGE NUMBER 147776
--------------
Received: (qmail 31579 invoked by uid 453); 27 Jul 2016 14:41:12 -0000
Received: from Unknown (HELO moi.pialasse.com) (127.0.0.2)
by moi.pialasse.com (qpsmtpd/0.84) with SMTP; Wed, 27 Jul 2016 10:41:12 -0400
Received: (qmail 31574 invoked by uid 453); 27 Jul 2016 14:41:10 -0000
Received: from Unknown (HELO moi.pialasse.com) (127.0.0.2)
by moi.pialasse.com (qpsmtpd/0.84) with SMTP; Wed, 27 Jul 2016 10:41:10 -0400
Received: (qmail 31564 invoked by uid 453); 27 Jul 2016 14:41:08 -0000
Received: from Unknown (HELO moi.pialasse.com) (127.0.0.2)
by moi.pialasse.com (qpsmtpd/0.84) with SMTP; Wed, 27 Jul 2016 10:41:08 -0400
Received: (qmail 31559 invoked by uid 453); 27 Jul 2016 14:41:07 -0000
Received: from Unknown (HELO moi.pialasse.com) (127.0.0.2)
by moi.pialasse.com (qpsmtpd/0.84) with SMTP; Wed, 27 Jul 2016 10:41:07 -0400
Received: (qmail 31552 invoked by uid 453); 27 Jul 2016 14:41:05 -0000
Received: from Unknown (HELO moi.pialasse.com) (127.0.0.2)
by moi.pialasse.com (qpsmtpd/0.84) with SMTP; Wed, 27 Jul 2016 10:41:05 -0400
...
Received: from Unknown (HELO moi.pialasse.com) (127.0.0.2)
by moi.pialasse.com (qpsmtpd/0.84) with SMTP; Wed, 27 Jul 2016 10:40:22 -0400
in only 2 minutes I had hundreds of lines , if it is days you have this message it might weight hundreds of megabytes.