You could try a backup ... if you're that scared !
I did it on 4 different servers, and they were all with in production, with intranet systems running, but all of them needed to be connected through ODBC.
Everything went just fine.
These upgraded packages are from Red Hat, and as far as I know, the e-smith team are using them with no modifications.
Now it's up to you.
PS: If you can you could first try it on a non productive server.