I think that when u backup to desktop it gets all user files (home dirs), email, installed contribs, custom templates, etc. But check the documentation on the website first.
There is a 2 GB limit on the backup file.
So if u have alot of user files, copy/backup them off the server first, to make the backup file less than 2 GB.
You can try just installing the new hardware and hook the HD up and see what happens. If the architecture is close enough, it will sort itself out.
If that does not work, install SME fresh, then do a restore from backup, easy.
hmmm....come to think of it...if you have an older version, booting from a CD of newer version, and choose upgrade....just might work.
there are many ways to skin a cat.
sspfunk