First, the message is simply fetchmail letting you know that it is not starting another instance of itself since another one is already running. Not an error, just a polite notification -- so you can track down why

The most likely cause is that 1) mail retrieval is scheduled for a short interval, such as five minutes, and 2) fetchmail is still active from the previous session. The causes for #2 are several, but the likely candidates are:
-- slow connection, lots of messages to download
-- slow connection, large message to download
-- fast connection, and really really really lots of or large message(s)

I've also seen the problem occur due to DNS issues. One ISP was "rebuilding" their DNS, and this is where the e-smith server was pointing for primary DNS resolution (dial-up). The mail system would attempt DNS lookups on domains hosted by this "rebuilding" DNS server, and would sometimes take 2-3 minutes to resolve. Multiply this by even two or three messages in one session, and the fetchmail process would run 5-10 minutes. With mail pickup scheduled every 5 minutes, we were seeing these messages frequently! Plus messages in both /var/log/messages and /var/log/qmail/* regarding the DNS problems.
Scott