Is it possible to add USB External Drive to RAID?
You can use ANY PARTITION to form a Linux SoftRaid. But why would you ?
The "R" in Raid is for redundancy
... USB is anything but a stable environment.
If your requirement still is "large continuous storage space" ...see my answer above!
Please don't overlook the fact that Linux isn't DOS, isn't limited to the letters of the alphabet "C: Z:" for storage
Adding a HD, making (several ?) partitions and mounting them where required will give you space where it's needed.
While LVM is the solution for the flexibility you ask for - it is mostly not even needed.
In SME I doubt you need more than the advice to:
"mount your HD into a new ibay"
... put your new stuff there...
Regards
Reinhold