Had a similar problem today on a server running a dedicated software package (SAM) that uses some database method (uses TPS extension files). Anyway, this has happened once before on this site - when users go to backup the software using that packages's utility, it says 'access denied - make sure all users are logged out' which they are, and the software reports no active users. I rang their support helpline and they said reboot the server. I never found out which file was locked, other than perhaps trial and error on 170 files - no thanks. I did arrange to reboot the server during lunchtime, and this fixed it, but I would like to know if I can find the offending 'open' file and be able to close it, like the M$ one in server 2003.