We have a user that is using Apple's MobileMe and has it configured to retrieve emails from our server using POP3. She is reporting that messages are showing up twice in the MobileMe webmail interface (and on her two laptops and Blackberry).
I would dismiss this an issue with MobileMe, but, every once in a great while, other users on Outlook/Outlook Express will temporiarly experience duplicate emails.
I haven't found anything meaningful in the logs, but I may have missed something. Would increasing the log level help? Which logs should I be focusing on?