@Mary: the WBL contrib cannot block by top-level domain, I believe, so that won't work for ".info"
If it can, I do not know the syntax. I have trouble getting users to train the Bayesian part of SpamAssassin so I don't use that. I'm using GeoIP with success, though I know that SMTP purists don't like it. (And I do understand why, I just find that it's effective in cutting down unwanted email and so far I've not had any complaints.)
It strikes me that with the explosion of TLDs we are going to see, that it would be extremely useful to be able to block by TLD.