Unless I'm greatly misunderstanding your question, what you do is install and use IRC clients as you would without the e-smith machine--it should have no effect on your ability to access IRC, and you shouldn't need to configure or modify anything on the e-smith box to make it work.
Did you mean you want the e-smith box to act as an IRC server? That isn't supported, and I don't know of anybody working on such a project at the moment.