I am having the same problem but the connection is always refused in Serveronly mode. But in Server / Gateway mode everything works fine. Ive tried several clients but no luck. Webmail works fine and port 110,25,143,443,995 are forwarded in my router. I cant use the SME server in Server/Gateway mode because my router always freeses up several times a day when Sme is in server/gateway mode (zyxel 660HW router) So any suggestions???