Thanks all for the replies.
This does help, even though I'm not positive about the *@*.tk topic or similar *@*.com I'm guessing would block anything that ended with .com so I should be able to easily test that out by simply sending my self some mail from my yahoo or hotmail account etc.
I read in the wiki for webmail / horde / blacklist that I could use the *@comcast.net etc. if i want my webmail account to blacklist all comcast.net incoming mail etc. But I was not sure about *@*.tk because I don't know if that blocks the whole .tk etc. But the syntax I think is different for a user/webmail/horde/blacklist then it is for the whole server settings.
I've read that wiki also and plan to impliment the newest blacklist as suggested in the wiki,however since I've been using the *@domain.com syntax in my webmail the spam is almost completely gone now, only about 1 or 2 spam mails a day now. It was getting up there at around like 20-40 spam mails, but I think I got it blocked now.
I use mostly webmail, cause I like the groupware sort of features with the file storage, and task list, and my contact manager could not be any better. I really can't complain about horde at all. I've been enjoying the reminder task feature as well.
I could probably just put *.tk and that might just work. I'll experiment with this some more and post back.